Publications

Anna-Maria Herzog, Katharina Göbel, Luigi Marongiu, Natalia Ruetalo, Marta Campos Alonso, Christian Leischner, Christian Busch , Markus Burkard, Ulrich M. Lauer, Paul P. Geurink, Klaus-Peter Knobeloch, Michael Schindler, Günter Fritz, Sascha Venturelli (2024) Compounds derived from Humulus lupulus inhibit SARS-CoV-2 papain-like protease and virus replication. Phytomedicine. 2024 Jan:123:155176 (doi.org/10.1016/j.phymed.2023.155176)

Hau, JL., Schleicher, L., Herdan, S., Simon, J., Seifert, J., Fritz, G., Steuber, J.(2024) Functionality of the Na+-translocating NADH:quinone oxidoreductase and quinol:fumarate reductase from Prevotella bryantii inferred from homology modeling. Arch Microbiol 206, 32 (doi.org/10.1007/s00203-023-03769-5)

Fritz, G., Kroneck, P.M.H., Steuber, J. The power supply for biological nitrogen fixation. Nat Chem Biol (2024). (doi.org/10.1038/s41589-024-01663-9)

Steuber J, Fritz G. The Na⁺-translocating NADH:quinone oxidoreductase (Na⁺-NQR): Physiological role, structure and function of a redox-driven, molecular machine. Biochim Biophys Acta Bioenerg. 2024 Jun 30;1865(4):149485. (doi: 10.1016/j.bbabio.2024.149485. Epub ahead of print. PMID: 38955304.)

Jin Gan, Adán Pinto-Fernández, Dennis Flierman, Jimmy J L L Akkermans, Darragh P O'Brien, Helene Greenwood, Hannah Claire Scott, Günter Fritz, Klaus-Peter Knobeloch, Jacques Neefjes, Hans van Dam, Huib Ovaa, Hidde L Ploegh, Benedikt M Kessler, Paul P Geurink, Aysegul Sapmaz (2023) USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism. PNAS Vol. 120, No. 50, 2023 (doi.org/10.1073/pnas.2315163120)

Dennis Peter Stegmann, Julia Steuber, Günter Fritz, Justyna Aleksandra Wojdyla, May Elizabeth Sharpe (2023) Fast fragment and compound screening pipeline at the Swiss Light Source. Methods in Enzymology, Volume 690, 2023, Pages 235-284 (doi: 10.1016/bs.mie.2023.08.005)

Herzog AM, Göbel K, Marongiu L, Ruetalo N, Alonso MC, Leischner C, Busch C, Burkard M, Lauer UM, Geurink PP, Knobeloch KP, Schindler M, Fritz G, Venturelli S. Phytomedicine. 2023 Oct 30;123:155176. doi: 10.1016/j.phymed.2023.155176. Online ahead of print.

Jann-Louis Hau, Hannes Kremser, Sabrina Knogl-Tritschler, Volker Stefanski, Julia Steuber, Günter Fritz (2023) Fast IMAC purification of non-tagged S100A8/A9 (calprotectin) from Homo sapiens and Sus scrofa. Protein Expression and Purification, Volumes 208-209, August 2023, 106275 (doi.org/10.1016/j.pep.2023.106275)

Schwedt I, Schöne K, Eckert M, Pizzinato M, Winkler L, Knotkova B, Richts B, Hau J-L, Steuber J, Mireles R, Noda-Garcia L, Fritz G, Mittelstädt C, Hertel R, Commichau FM (2023) The low mutational flexibility of the EPSP synthase in Bacillus subtilis is due to a higher demand for shikimate pathway intermediates. Environ Microbiol (doi.org/10.1111/1462-2920.16518)

Hau J-L, Kaltwasser S, Muras V, Casutt MS, Vohl G, Claußen B, Steffen W, Leitner A, Bill E, Cutsail III GE, DeBeer S, Vonck J, Steuber J, Fritz G (2023) Conformational coupling of redox-driven Na+-translocation in Vibrio cholerae NADH:quinone oxidoreductase. Nat Struct Mol Biol (doi.org/10.1038/s41594-023-01099-0)

Steiner ST, Maisuls I, Junker A, Fritz G, Faust A, Strassert CA (2023) Concerning the photophysics of fluorophores towards tailored bioimaging compounds: a case study involving S100A9 inflammation markers. Photochem Photobiol Sci. 22:2093-2104. (doi: 10.1007/s43630-023-00432-2)

Andrej Trautmann, Lena Schleicher, Ariane Koch, Johannes Günther, Julia Steuber, Jana Seifert (2023) A shift towards succinate-producing Prevotella in the ruminal microbiome challenged with monensin. Proteomics, Proteomics and Systems Biology, 2023, Vol. 23 (doi.org/10.1002/pmic.202200121)

Jakub W. Kaminski, Laura Vera, Dennis P. Stegmann, Jonatan Vering, Deniz Eris, Kate M. L. Smith, Chia-Ying Huang, Nathalie Meier, Julia Steuber, Meitian Wang, Günter Fritz, Justyna A. Wojdyla and May E. Sharpe (2022) Fast fragment- and compound-screening pipeline at the Swiss Light Source. Acta Cryst. D78, 2022  (doi.org/10.1107/S2059798322000705)

Basmanav FB, Cesarato N, Kumar S, Borisov O, Kokordelis P, Ralser DJ, Wehner M, Axt D, Xiong X, Thiele H, Dolgin V, Gossmann Y, Fricker N, Dewenter MK, Weller K, Suri M, Reichenbach H, Oji V, Addor MC, Ramirez K, Stewart H, Garcia Bartels N, Weibel L, Wagner N, George S, Kilic A, Tantcheva-Poor I, Stewart A, Dikow N, Blaumeiser B, Medvecz M, Blume-Peytavi U, Farrant P, Grimalt R, Bertok S, Bradley L, Eskin-Schwartz M, Birk OS, Bygum A, Simon M, Krawitz P, Fischer C, Hamm H, Fritz G, Betz RC. (2022) Assessment of the Genetic Spectrum of Uncombable Hair Syndrome in a Cohort of 107 Individuals. JAMA Dermatol. 158:1245-1253. (doi: 10.1001/jamadermatol.2022.2319)

Bishir M, Tariq M, Wüst D, Schleicher L, Steuber J, Kruse A (2021) Comparative Electricity Generation by Two Locally Produced Corncob Pyrochar Electrodes and Graphite using Microbial Fuel Cell Technology. Int. J. of Renewable Energy Researc  Vol 11, No 4 (2021) (doi.org/10.20508/ijrer.v11i4.12572.g8322)

Trautmann A, Schleicher L, Pfirrmann J, Boldt C, Steuber J, Seifert J (2021) Na+-coupled respiration and reshaping of extracellular polysaccharide layer counteract monensin-induced cation permeability in Prevotella bryantii B14. Int. J. Mol. Sci. 2021, 22, 10202. (doi.org/10.3390/ijms221910202)

Schleicher L, Trautmann A, Stegmann D, Fritz G, Gätgens J, Bott M, Hein S, Simon J, Seifert J, Steuber J (2021) A sodium-translocating module linking succinate production to formation of a membrane potential in Prevotella bryantii. Appl. Environ. Microbiol. Epub 2021/09/01. (doi: 10.1128/AEM.01211-21)

Schleicher L, Herdan S, Fritz G, Trautmann A, Seifert J, Steuber J. (2021) Central Carbon Metabolism, Sodium-Motive Electron Transfer, and Ammonium Formation by the Vaginal Pathogen Prevotella bivia. International Journal of Molecular Sciences. 2021; 22(21):11925. (doi.org/10.3390/ijms222111925)

Moreira, G.G., Cantrelle, FX., Quezada, A., Carvalho, F.S., Cristóvão, J.S., Sengupta, U., Puangmalai, N., Carapeto, A.P., Rodrigues, M.S., Cardoso, I., Fritz, G., Herrera, F., Kayed, R., Landrieu, I., Gomes, C.M. (2021) Dynamic interactions and Ca2+-binding modulate the holdase-type chaperone activity of S100B preventing tau aggregation and seeding. Nat Commun 12:6292 (doi: 10.1038/s41467-021-26584-2)

Dupont, V., Al-Rifai, R., Poitevin, G. , Ortillon, J., Jayyosi, L., Terryn, C., Francois, C., Rieu, P., Fritz, G., Boulagnon-Rombi, C., Fichel, C., Schmidt, A.M., Tournois, C., Nguyen, P., Touré, F. (2021) AgeR deletion decreases soluble fms-like tyrosine kinase 1 production and improves post-ischemic angiogenesis in uremic mice. Angiogenesis 24:47-55 (doi: 10.1007/s10456-020-09747-5)

Cristóvão, J.S., Moreira, G.G., Rodrigues, F.E.P., Carapeto, A.P., Rodrigues, M.S., Cardoso, I., Ferreira, A.E.N., Machuqueiro, M., Fritz, G., Gomes, C.M. (2021) Cu2+-binding to S100B triggers polymerization of disulfide cross-linked tetramers with enhanced chaperone activity against amyloid-β aggregation. Chem Commun (Camb) 57:379-382 (doi: 10.1039/d0cc06842j)

 Trautmann A., Schleicher L., Deusch S., Gätgens J., Steuber J., Seifert J. (2020) Short-chain fatty acids modulate metabolic pathways and membrane lipids in Prevotella bryantii B14. Proteomes 8:28 (doi:10.3390/proteomes8040028)

Reiske, L., Schmucker, S.S., Steuber, J., Toulouse, C., Pfaffinger, B., Stefanski, V. (2020) Interkingdom cross-talk in times of stress: Salmonella Typhimurium grown in the presence of catecholamines inhibits porcine immune functionality in vitro. Front. Immunol.11:572056 . (doi: 10.3389/fimmu.2020.572056)

Agarwal S, Bernt M, Toulouse C, Kurz H, Pfannstiel J, D'Alvise P, Hasselmann M, Block AM, Häse CC, Fritz G, Steuber J. Impact of Na+-Translocating NADH:Quinone Oxidoreductase on Iron Uptake and nqrM Expression in Vibrio cholerae. J Bacteriol. 2020 Jan 15;202(3) (doi: 10.1128/JB.00681-19)

Schleicher, L., Fritz, G., Seifert, J., Steuber J.,Anoxic cell rupture of Prevotella bryantii by high-pressure homogenization protects the Na+-translocating NADH:quinone oxidoreductase from oxidative damage, l. Arch Microbiol 202:12631266 (doi: 10.1007/s00203-019-01805-x)

Reiske L, Schmucker S, Pfaffinger B, Weiler U, Steuber J, Stefanski V., Intravenous Infusion of Cortisol, Adrenaline, or Noradrenaline Alters Porcine Immune Cell Numbers and Promotes Innate over Adaptive Immune Functionality, J Immunol. 2020 May 11 (doi:10.4049/jimmunol.2000269)

Degani G. , Altomare A. , Digiovanni S. , Arosio B. , Fritz G. , Raucci A., Aldini G., Popolo L. Prothrombin is a binding partner of the human Receptor of Advanced Glycation End products, J Biol Chem  2020, Vol. 295 (35): 12498-12511 (doi: 10.1074/jbc.RA120.013692)

Han Z.,  Angerer H., Bischoff I., Qin Y., Stegmann D., Tuz K., Amati A. M., Fritz G., Juárez O., Fuerst R., Lashley D., Nasiri, H. R. Concise synthesis of 1,4-benzoquinone based natural products as mitochondrial complex I substrates and substrate-based inhibitors ChemMedChem 2020, in press (doi.org/10.1002/cmdc.202000307)

Ortillon, J., Hézard, N., Belmokhtar, K., Kawecki, C., Terryn, C., Fritz, G., Kauskot, A., Schmidt, A.M., Rieu, P., Nguyen, P., Maurice, P., Touré, F. (2020) Receptor for Advanced Glycation End Products is Involved in Platelet Hyperactivation and Arterial Thrombosis during Chronic Kidney Disease. Thromb Haemost 120:1300-1312 (doi: 10.1055/s-0040-1714101)

Schmidt M, Wiese S, Adak V, Engler J, Agarwal S, Fritz G, Westermark P, Zacharias M, Fändrich M, Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis. ,Nat Commun. 2019 Nov 1;10(1):5008 (doi: 10.1038/s41467-019-13038-z)

Reiske, L., Schmucker, S., Steuber, J., Stefanski, V. (2019) Differential effects of glucocorticoids and catecholamines on in vitro functionality of porcine blood immune cells. Animals 9:545 (doi: 10.3390/ani9080545)

Heyer, C.M.E., Schmucker, S., Burbach, K., Weiss, E., Eklund, M., Aumiller, T., Capezzone, F., Steuber, J., Rodehutscord, M., Hoelzle, L.E., Seifert, J., Mosenthin, R., Stefanski, V. (2019) Phytate degradation, intestinal microbiota, microbial metabolites, and immune values are changed in growing pigs fed diets with varying calcium-phosphorus concentration and fermentable substrates. J. Anim. Physiol. Anim. Nutr. (Berl.) 103(4): 1185-1197(doi: 10.1111/jpn.13088)

Radamaker L, Lin Y-H, Annamalai K, Huhn S, Hegenbart U,  Schönland SO, Fritz G, Schmidt M, and Fändrich M (2019) Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis. Nature Communications 2019 Mar 20;10(1):1103 (doi:10.1038/s41467-019-09032-0)

Belmokhtar K, Ortillon J, Jaisson S, Massy ZA, Boulagnon Rombi C, Doué M, Maurice P, Fritz G, Gillery P, Schmidt AM, Rieu P, Touré F (2019) Receptor for advanced glycation end products: a key molecule in the genesis of chronic kidney disease vascular calcification and a potential modulator of sodium phosphate co-transporter PIT-1 expression. Nephrol Dial Transplant. Dec 1;34(12)2018-2030 (doi: 10.1093/ndt/gfz012)

Toulouse, C., Schmucker, S., Metesch, K., Pfannstiel, J., Michel, B., Starke, I., Möller, H.M., Stefanski, V., Steuber, J. (2019) Mechanism and impact of catecholamine conversion by Vibrio cholerae. Biochim. Biophys. Acta Bioenergetics 1860(6):478-487 (doi: 10.1016/j.bbabio.2019.04.003)

Deusch, S., Bok, E., Schleicher, L., Seifert, J., Steuber, J. (2019) Occurence and function of the Na+ -translocating NADH:quinone oxidoreductase in Prevotella spp. Microorganisms 7:117 (doi: 10.3390/microorganisms7050117)

Schleicher, L., Muras, V., Claussen, B., Pfannstiel, J., Blombach, B., Dibrov, P., Fritz, G., Steuber, J. (2018) Vibrio natriegens as host for expression of multisubunit membrane protein complexes. Front. Microbiol.9:2537 (doi: 10.3389/fmicb.2018.02537)

Toulouse, C., Metesch, K., Pfannstiel, J., Steuber, J. (2018) Metabolic reprogramming of Vibrio cholerae impaired in respiratory NADH oxidation is accompanied with increased copper sensitivity. J Bacteriol 200:e00761-17 (doi: 10.1128/JB.00761-17)

Ralser, DJ;  Takeuchi, H; Fritz, G; Basmanav, FB; Effern, M; Sivalingam, S ; El-Shabrawi-Caelen, L; Degirmentepe, EN; Kocatürk, E; Singh, M; Booken, N; Spierings, NMK; Schnabel, V; Heineke, A; Knuever, J; Wolf, S; Wehner, M; Tronnier, M; Tantcheva-Poor, Ia; Wenzel, J; Oij, V; Has, CMD; Hölzel, M; Frank, J; Haltiwanger, RS.; Betz, RC (2018) Altered Notch Signaling in Dowling-degos Disease: Additional mutations in POGLUT1 and further insights into disease pathogenesis.  J Invest Dermatol. accepted for publication (doi.org/10.1016/j.jid.2018.10.030)

Basters A, Knobeloch KP, Fritz G (2018) USP18 - a multifunctional component in the Interferon response. Biosci Rep. pii: BSR20180250. (doi: 10.1042/BSR20180250) Cristóvão JS, Morris VK, Cardoso I, Leal SS, Martínez J, Botelho HM, Göbl C, David R, Kierdorf K, Alemi M, Madl T, Fritz G, Reif B, Gomes CM (2018) The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation. Sci Adv. 4(6):eaaq1702 (doi: 10.1126/sciadv.aaq1702) Basters A, Knobeloch KP, Fritz G. (2018) How USP18 deals with ISG15-modified proteins: structural basis for the specificity of the protease. FEBS J. 285:1024-1029. (doi: 10.1111/febs.14260)

 Muras, V., Claussen, B., Nasiri, H., Fritz, G., Steuber, J. (2017) A miniaturized assay for kinetic characterization of the Na+ -translocating NADH:ubiquinone Oxidoreductase  (NQR) from Vibrio cholerae. Anal. Biochem. 537:56-59 (doi: 10.1016/j.ab.2017.08.025)

Toulouse, C., Häse, C.C., Steuber, J. (2017) Chloroform-free permeabilization for improved detection of β-galactosidase activity in Vibrio cholerae. J. Microbiol. Meth., 137:1-2 (doi: 10.1016/j.mimet.2017.03.011)

Toulouse, C., Claussen, B., Muras, V., Fritz, G., Steuber, J. (2017) Strong pH dependence of coupling efficiency of the Na+ - translocating NADH:quinone oxidoreductase (Na+ -NQR) of Vibrio cholerae. Biol. Chem. 398:251-260 (doi: 10.1515/hsz-2016-0238)

Reppin F, Cochet S, El Nemer W, Fritz G, Schmidt G. (2017) High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein. Toxins 10(1). pii: E3. (doi: 10.3390/toxins10010003)

Ralser DJ, Lestringant GG, Du-Thanh A, Kokordelis P, Fischer J, Basmanav FBÜ, Wolf S, Thiele H, Altmüller J, Nürnberg P, Oji V, Fritz G, Frank J, Betz RC (2017) Functional implications of novel ADAM10 mutations in reticulate acropigmentation of Kitamura. Br J Dermatol. 177(6):e340-e343. (doi: 10.1111/bjd.16024)

Basters A, Geurink PP, Röcker A, Witting KF, Tadayon R, Hess S, Semrau MS, Storici P, Ovaa H, Knobeloch KP, Fritz G (2017) Structural basis of the specificity of USP18 toward ISG15. (2017) Nat Struct Mol Biol. 24, 270-278 (doi: 10.1038/nsmb.3371)

Degani G, Altomare AA, Colzani M, Martino C, Mazzolari A, Fritz G, Vistoli G, Popolo L, Aldini G (2017) A capture method based on the VC1 domain reveals new binding properties of the human receptor for advanced glycation end products (RAGE) Redox Biology 11, 275-285 (doi: 10.1016/j.redox.2016.12.017)

Muras, V., Dogaru-Kinn, P., Minato, Y., Häse, C.C., Steuber, J. (2016) The Na+ -translocating NADH:quinone oxidoreductase (Na+ -NQR) enhances oxidative stress in the cytoplasm of Vibrio cholerae. J. Bacteriol. 198: 2307-2317 (doi: 10.1128/JB.00342-16)

Vorburger, T.; Nedielkov, R.; Brosig, A.; Bok, E.; Schunke, E.; Steffen, W.; Mayer, S.; Götz, F.; Möller, H.M.; Steuber, J. (2016) Role of the Na+-translocating NADH:quinone oxidoreductase in voltage generation and Na+ extrusion in Vibrio cholerae. Biochim Biophys Acta (Bioenergetics), 1857: 473-478 (doi: 10.1016/j.bbabio.2015.12.010)

Di Maggio S, Gatti E, Liu J, Bertolotti M, Fritz G, Bianchi ME, Raucci A. (2016) The mouse-specific splice variant mRAGE_v4 encodes a membrane-bound RAGE that is resistant to shedding and does not contribute to the production of soluble RAGE. PlosOne 11:e0153832 (doi: 10.1371/journal.pone.015383)

Halang, P., Toulouse, C., Geißel, B., Michel, B., Flauger, B., Müller, M., Voegele, R.T., Stefanski, V., Steuber, J. (2015) Response of Vibrio cholerae towards the catecholamine hormones epinephrine and norepinephrine. J. Bacteriol. 197: 3769-3778 (doi: 10.1128/JB.00345-15)

Halang, P., Vorburger, T., Steuber, J. (2015) Serine 26 in the PomB subunit of the flagellar motor is essential for hypermotility of Vibrio cholerae. PLOSone, 10(4): e0123518 (doi: 10.1371/journal.pone.0123518)

Mayer, S., Steffen, W., Steuber, J., Götz, F. (2015) The Staphylococcus aureus NuoL-like protein MpsA contributes to the generation of membrane potential. J. Bacteriol. 197:794-806 (doi: 10.1128/JB.02127-14)

Fritz G and Kroneck PMH. Sulfate To Go (2015) Science. 350:1476-7 (doi: 10.1126/science.aad8139)

Steuber J, Vohl G, Muras V, Toulouse C, Claußen B, Vorburger T, Fritz G (2015) The structure of Na+-translocating of NADH:ubiquinone oxidoreductase of Vibrio cholerae: implications on coupling between electron transfer and Na+ transport. Biol Chem. 396:1015-30. (doi: 10.1515/hsz-2015-0128)

Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, Basters A, Staszewski O, Brendecke SM, Spieß A, Tay TL, Kreutz C, Timmer J, Blank T, Fritz G, Biber K, Lang R, Malo D, Merkler D, Mathias Heikenwalder M, Knobeloch KPK, Prinz M (2015) USP18 lack in microglia causes a destructive Interferonopathy of the mouse brain. Embo J 34:1612-29  (doi: 10.15252/embj.201490791)

Degani G, Colzani M, Tettamanzi A, Sorrentino L, Aliverti A, Fritz G, Aldini G, Popolo L. (2015) An improved expression system for the VC1 ligand binding domain of the receptor for advanced glycation end products in Pichia pastoris. Protein Expr Purif. 114:48-57 (doi.org/10.1016/j.pep.2015.06.012)

Gollasch B, Basmanav FB, Nanda A, Fritz G, Mahmoudi H, Thiele H, Wehner M, Wolf S, Altmüller J, Nürnberg P, Frank J, Betz RC. (2015) Identification of a novel mutation in RIPK4 in a kindred with phenotypic features of Bartsocas-Papas and CHAND syndromes. Am J Med Genet A. 167:2555-62. (doi.org/10.1002/ajmg.a.37233)

Steuber, J., Vohl, G., Casutt, M.S., Vorburger, T., Diederichs, K., Fritz, G. (2014) Structure of the V.cholerae Na+-pumping NADH:quinone oxidoreductase. Nature, 516: 62-67 (doi: 10.1038/nature14003)

Muras, V., Claussen, B., Karuppasamy, M., Schaffitzel, C., Steuber, J. (2014) Continuous fluorescence based measurement of redox driven sodium ion translocation. Anal. Biochem., 459:53-55 (doi: 10.1016/j.ab.2014.05.012)

Vohl, G., Nedielkov, R., Claussen, B., Casutt, M., Vorburger, T., Diederichs, K., Möller, H.M., Steuber, J., Fritz, G. (2014) Crystallization and preliminary analysis of the subunits NqrA and NqrC of the Na+ -translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae. Acta Cryst. F, 70, 987–992 (doi: 10.1107/S2053230X14009881)

Minato, Y., Fassio, S.R., Kirkwood, J.S., Halang, P., Quinn, M.J., Faulkner, W.J., Aagesen, A.M., Steuber, J., Stevens, J.F., Häse, C.C. (2014) Roles of the sodium-translocating NADH-quinone oxidoreductase (NQR) on Vibrio cholerae metabolism, motility and osmotic stress resistance. PLOSone, 9(5): e97083 (doi: 10.1371/journal.pone.0097083)

Steuber, J., Halang, P., Vorburger, T., Steffen, W., Vohl, G., Fritz, G. (2014) Central role of the Na+ -translocating NADH:quinone oxidoreductase (Na+ -NQR) in sodium bioenergetics of Vibrio cholerae. Biol. Chem., 395, 1389-1399 (doi: 10.1515/hsz-2014-0204)

Basmanav, F.B, Fritz, G., Lestringant, G.G., Pachat, D., Hoffjan, S., Fischer,J., Wehner, M., Wolf, S., Thiele, H., Altmüller, J., Pulimood, S.A., Rütten, A., Kruse, R., Hanneken, S., Frank, J., Danda, S., Bygum, A., and Betz, R.C.1 (2014) Pathogenicity of POFUT1 in Dowling-Degos disease: novel mutations and clinical overlap with reticulate acropigmentation of Kitamura The J. of Invest. Dermatology 135:615-8 (doi.org/10.1038/jid.2014.406)

Basters, A., Geurink, P.P., El Oualid, F., Ketscher, L., Casutt, M.S., Krause, E., Ovaa, H., Knobeloch, K.P., Fritz, G. (2014) Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15.  FEBS J. 281:1918-28 (doi.org/10.1111/febs.12754)

Sessa, L., Gatti, E, Antonelli, A, Catucci, A., Fritz, G., Raucci, A., Bianchi, M.E. (2014) The receptor for advanced glycosylation end-products (RAGE) is only present in mammals, and belongs to a family of cell adhesion molecules (CAMs). PLoS ONE, 9:e86903 (doi: 10.1371/journal.pone.0086903)

Basmanav FB, Oprisoreanu AM, Pasternack SM, Thiele H, Fritz G, Wenzel J, Größer L, Wehner M, Wolf S, Fagerberg C, Bygum A, Altmüller J, Rütten A, Parmentier L, El Shabrawi-Caelen L, Hafner C, Nürnberg P, Kruse R, Schoch S, Hanneken S, Betz RC (2014). Mutations in POGLUT1, Encoding Protein O-Glucosyltransferase 1, Cause Autosomal-Dominant Dowling-Degos Disease. Am J Hum Genet. 94:135-43 (doi: 10.1016/j.ajhg.2013.12.003)

Nedielkov, R., Steffen, W., Steuber, J., Möller, H. (2013) NMR reveals double occupancy of quinone-type ligands in the catalytic quinone binding site of the Na+-translocating NADH:quinone oxidoreductase from Vibrio cholerae. J. Biol. Chem., 288:30597-30606 (doi: 10.1074/jbc.M112.435750)              

Halang, P., Leptihn, S., Meier, T., Vorburger, T., Steuber, J. (2013) The function of the Na+-driven flagellum of Vibrio cholerae is determined by osmolality and pH. J. Bacteriol., 195: 4888-4899 (doi: 10.1128/JB.00353-13)

Steffen, W., Steuber, J. (2013) Cation transport by the respiratory NADH:quinone oxidoreductase (complex I): facts and hypotheses. Biochem. Soc. Trans., 41, 1280-1287 (doi: 10.1042/BST20130024)

Sousa, P.M., Videira, M.A., Vorburger, T., Silva, S.T., Moir, J.W., Steuber, J., Melo, A.M. (2013) The novel NhaE-type Na+/H+ antiporter of the pathogenic bacterium Neisseria meningitidis. Arch. Microbiol. 195: 211-217 (doi: 10.1007/s00203-012-0856-4)

Carvalho, S.B., Botelho, H.M., Leal, S.S., Cardoso, I., Fritz, G., and Gomes, C.M. (2013) Intrinsically disordered and aggregation prone regions underlie b-aggregation in S100 proteins. PLoS ONE 8: e76629 (doi: 10.1371/journal.pone.0076629)

Kierdorf, K. and Fritz, G. (2013) RAGE regulation and signaling in inflammation and beyond J. Leukocyte Biol. 94:55-68. (doi.org/10.1189/jlb.1012519)

Damo, S.M., Kehl-Fie, T.E., Sugitania, N., Holta, M.E., Rathia, S., Betz, C., Hencha, L., Fritz, G., Skaar, E.P., Chazin, W.J. (2013) Molecular basis for manganese sequestration by calprotectin and its role in the innate immune response to invading bacterial pathogens. Proc. Natl. Acad. Sci. U S A.  110, 3841-3846 (doi: 10.1073/pnas.1220341110)

Kierdorf, K., Erny, D, Goldmann, T., Sander, V., Schulz, C., Gomez Perdiguero, E., Wieghofer, P., Heinrich, A., Riemke, P., Hölscher, C., Müller, D.N., Luckow, B., Brocker, T., Debowski, K. Fritz, G., Opdenakker, G., Diefenbach, A., Biber, K., Heikenwälder, M., Geissmann, F., Rosenbauer, F., and Prinz, M. (2013) Microglia emerge from erythromyeloid precursors via PU.1 and IRF-8 dependent pathways. Nat. Neurosci, 16, 273-280 (doi: 10.1038/nn.3318)

Kulic, Z., Fritz, G. and Möller, H.  (2013) 1H, 13C, and 15N resonance assignments of the second immunoglobulin domain of neurolin from Carassius auratus.  Biomol. NMR Assign. 7, 65-67 .(doi.org/10.1007/s12104-012-9379-9)

Parey, K., Fritz, G., Ermler, U. and Kroneck, P.M.H. (2013) Conserving energy with sulfate around 100°C – structure and mechanism of key metal enzymes in hyperthermophilic Archaeoglobus fulgidus. Metallomics 5, 302-317 (doi: 10.1039/C2MT20225E)

Lunin, V.Y., Lunina, N.L., Casutt, M.S., Knoops, K., Schaffitzel, C., Steuber, J., Fritz, G., Baumstark, M.W. (2012) Low resolution structure determination of Na+ -pumping NADH:ubiquinone oxidoreductase from Vibrio cholerae by ab initio phasing and electron microscopy. Acta Cryst. D, 68:724-731 (doi: 10.1107/S0907444912012012)

Casutt, M.S., Schlosser, A., Buckel. W., Steuber, J. (2012) The Single NqrB and NqrC Subunits in the Na+-Translocating NADH:Quinone Oxidoreductase (Na+-NQR) From  Vibrio cholerae Each Carry One Covalently Attached FMN. Biochim. Biophys. Acta (Bioenergetics) 1817: 1817–1822 (doi: 10.1016/j.bbabio.2012.02.012)

Botelho, H.M., Leal, S.S., Cardoso, I., Yanamandra, K., Morozova-Roche, L.A., Fritz, G., Gomes, C.M. (2012) S100A6 amyloid fibril formation is calcium-modulated and enhances superoxide dismutase-1 (SOD1) aggregation. J Biol Chem 287, 42233-42 (doi: 10.1074/jbc.M112.396416)

Basters, A., Ketscher, L., Deuerling, E., Arkona, C., Rademann, J., Knobeloch, K.P.*, and Fritz, G. (2012) High yield expression of catalytically active USP18 (UBP43) using a Trigger Factor fusion system. BMC Biotechnol. 12, 56 (doi: 10.1186/1472-6750-12-56)

Meloni, G., Crameri, A., Fritz, G., Davies, P., Brown, D.R., Peter M.H. Kroneck, P.M.H. and Vasák, M. (2012) The Catalytic Redox Activity of Prion Protein-Cu(II) is Controlled by Metal Exchange with the Zn(II)-thiolate Clusters of Zn7Metallothionein-3. Chem. Biochem. 13, 1261-5 (doi.org/10.1002/cbic.201200198)

Touré,F., Fritz, G., Li, Q., Rai, V., Daffu, G., Zou, Y.S., Rosario, R., Ramasamy, R., Alberts, A.S., Shi Fang Yan, S.F., and Schmidt, A.M. (2012) The Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative & Signal Transduction Pathways. Circulation Res, 10, 1279-93 (doi: 10.1161/CIRCRESAHA.111.262519)

Wild, C.A., Bergmann, C., Fritz, G., Kandlen I., Schuler, P., Hoffmann, T.K., Lot, R., Westendorf, A., Brandau, S., and Lang, S. (2012) HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells.  Int. Immunol.  24, 485-94. (doi.org/10.1093/intimm/dxs051)

Deane, R., Singh, I., Sagare, A.P, Bell, R.D., Ross, N.T., LaRue, B., Love, L., Perry, S., Paquette, N., Deane,R.J., Thiyagarajan, M., Zarcone T., Fritz G., Friedman A.E., Miller B.L., and Zlokovic B.V. (2012) A multimodal RAGE-specific inhibitor reduces amyloid ß mediated brain disorder in a mouse model of Alzheimer disease. J. Clin. Invest. 122, 1377-92. (doi: 10.1172/JCI58642)

Koch, M. and Fritz, G. (2012) The structure of Ca2+-loaded S100A2 at 1.3 Å resolution FEBS J. 279, 1799-810 (doi: 10.1111/j.1742-4658.2012.08556.x)

Casutt, M.S., Nedielkov, R., Wendelspiess, S., Vossler, S., Gerken, U., Murai, M., Miyoshi, H., Möller, H., Steuber, J. (2011) Localization of ubiquinone-8 in the Na+ -pumping NADH:quinone oxidoreductase from Vibrio cholerae, J. Biol. Chem., 286:40075-40082 (doi: 10.1074/jbc.M111.224980)

Haupt, C., Bereza, M., Kumar, S.T., Kieninger, B., Morgado, I., Hortschansky, P., Fritz, G., Röcken C, Horn U, Fändrich M.  (2011) Pattern recognition with a fibril-specific antibody fragment reveals the surface variability of natural amyloid fibrils  J. Mol. Biol. 408, 529-40 (doi: 10.1016/j.jmb.2011.02.032)

Ostendorp, T., Diez, J., Heizmann, C.W., Fritz, G.  (2011) The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping. BBA Mol. Cell. Res. 1813, 1083-91 (doi: 10.1016/j.bbamcr.2010.10.006)

Fritz, G.  (2011) RAGE: a single receptor fits multiple ligands. Trends in Biochem. Sci 36, 625-32 (doi: 10.1016/j.tibs.2011.08.008

Casutt, M.S., Wendelspiess, S., Steuber, J., Fritz, G. (2010) Crystallization of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae. Acta Cryst. F66, 1677-1679 (doi: 10.1107/S1744309110043125)

Casutt, M.S., Huber, T., Brunisholz, R., Tao, M., Fritz, G., Steuber, J. (2010) Localization and function of the membrane-bound riboflavin in the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) from Vibrio cholerae, J. Biol. Chem., 285:27088-27089 (doi: 10.1074/jbc.M109.071126)

Steffen, W., Gemperli A.C., Cvetesic, N., Steuber, J. (2010) Organelle-specific expression of subunit ND5 of human complex I (NADH dehydrogenase) alters cation homeostasis in Saccharomyces cerevisiae, FEMS Yeast Research, 10:648-659 (doi: 10.1111/j.1567-1364.2010.00643.x)

Batista, A.P., Fernandes, A.S., Louro, R.O., Steuber, J., Pereira, M.M. (2010) Energy conservation by Rhodothermus marinus respiratory Complex I, Biochim. Biophys. Acta (Bioenergetics), 1797:509-515 (doi: 10.1016/j.bbabio.2010.01.020)

Fritz, G. Botelho, H.M, Morozova-Roche, L., Gomes, C. (2010) Natural and amyloid self-assembly of S100 proteins: structural basis of functional diversity.  FEBS Journal 277, 4578-90  (doi: 10.1111/j.1742-4658.2010.07887.x)

Koch M., Diez J., Wagner A. and Fritz, G. (2010) Crystallization and Calcium/Sulfur SAD phasing of the human EF-hand protein S100A2 Acta Cryst. F 66, 1032-6 (doi: 10.1107/S1744309110030691)

Koch M., Chitayat S., Dattilo B.M., Schiefner A. Diez J., Chazin W.J. and Fritz G. (2010) Structural basis for ligand recognition and activation of RAGE. Structure 18, 1342-52 (doi: 10.1016/j.str.2010.05.017)

Vorburger, T., Stein, A., Kaim, G., Steuber, J. (2009) Functional role of a conserved aspartic acid residue in the motor of the Na+-driven flagellum from Vibrio cholerae. Biochim. Biophys. Acta (Bioenergetics), 1787: 1198–1204 (doi: 10.1016/j.bbabio.2009.05.015)

Botelho, H.M., Koch, M., Fritz, G., Gomes., C. M. (2009) Metal ions modulate the folding and stability of the tumor suppressor protein S100A2.  FEBS J. 276, 1776-86 (doi.org/10.1111/j.1742-4658.2009.06912.x)

Austermann, J., Nazmi, J.A., Heil, A., Fritz, G., Kolinski, M., Filipek, S., and Gerke, V. (2009) Generation and characterization of a novel, permanently active S100P mutant BBA Mol. Cell Res. 1791, 1078-85 (doi.org/10.1016/j.bbamcr.2008.11.012)

Leclerc, E., Fritz, G., Vetter, S. and Claus. W. Heizmann, C.W. (2009) Binding of S100 proteins to RAGE: an update. BBA Mol. Cell Res. 1793, 993-1007 (doi.org/10.1016/j.bbamcr.2008.11.016)

Lin, P.-C., Puhar, A., Steuber, J. (2008) NADH oxidation drives respiratory Na+ transport in mitochondria from Yarrowia lipolytica. Arch. Microbiol.,190:471-480 (doi: 10.1007/s00203-008-0395-1)

Tao, M., Casutt, M.S., Fritz, G., Steuber, J. (2008) Oxidant-induced formation of a neutral flavosemiquinone in the Na+ -translocating NADH:quinone oxidoreductase (Na+ -NQR) from Vibrio cholerae, Biochim. Biophys. Acta (Bioenergetics), 1777:696-702 (doi: 10.1016/j.bbabio.2008.04.006)

Tao, M., Fritz, G., Steuber, J. (2008) The Na+ -translocating NADH:quinone oxidoreductase (Na+ -NQR) from Vibrio cholerae enhances insertion of FeS into the overproduced NqrF subunit. J. Inorg. Biochem., 102:1366-1372 (doi: 10.1016/j.jinorgbio.2008.01.009)

Tao, M., Casutt, M. Fritz, G., Steuber, J. (2008) Oxidant-induced formation of a neutral flavosemiquinone in the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) from Vibrio cholerae. BBA Bioenergetics 1777, 696-702 (doi: 10.1016/j.bbabio.2008.04.006)

Koch, M., Diez, J., Fritz, G.* (2008) The Crystal structure of human Ca2+-free S100A2 at 1.6 Å resolution. J. Mol. Biol. 378, 931-940 (doi.org/10.1016/j.jmb.2008.03.019)

Drees, C., Stuermer, C.A.O., Möller, H.M. and Fritz, G. (2008) Expression and purification of neurolin immunoglobulin domain 2 from Carrassius auratus (goldfish) in Escherichia coli. Protein Expression and Purification 59, 47-54  (doi.org/10.1016/j.pep.2007.12.015)

Uetz-von Allmen E., Koch M., Fritz G., and Legler, D.F. (2008) V-domain of RAGE interacts with AGEs on prostate carcinoma cells. Prostate 68, 748-58. (doi.org/10.1002/pros.20736)

Thaa B., Zahn R., Matthey U, Kroneck P.M.H., Bürkle A., and Fritz G. (2008) The deletion of amino acids 114-121 in the TM1 domain of mouse prion protein stabilizes its conformation but does not affect the overall structure. BBA Mol. Cell Res. 1783, 1076-84. (doi.org/10.1016/j.bbamcr.2007.11.007)

Gemperli, A. C., Schaffitzel, C., Jacob, C., Steuber, J. (2007) Transport of K+ and Na+ by an antiporter-related subunit from the Escherichia coli NADH dehydrogenase I produced in Saccharomyces cerevisiae. Arch. Microbiol., 188: 509-521

Lin, P.-C., Türk, K., Häse, C. Fritz, G., Steuber, J. (2007) Quinone reduction by the Na+ -translocating NADH dehydrogenase (Na+-NQR) promotes extracellular superoxide production in Vibrio cholerae. J. Bacteriol., 189:3902-3908 (doi: 10.1128/JB.01651-06)

Leclerc E., Fritz, G., Weibel, M., Heizmann,C.W., and Galichet, A. (2007) S100B and S100A6 differentially modulate cell survival through their interaction with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains. J. Biol. Chem. 282, 31317-31. (doi: 10.1074/jbc.M703951200)

Ostendorp, T., Leclerc E., Galichet, A., Koch. M, Demling,N., Weigle, B., Heizmann,C.W., Kroneck, P.M.H. and Fritz, G. (2007) Structural and functional insights into RAGE activation by multimeric S100B. The EMBO Journal 26, 3868-3878. (doi: 10.1038/sj.emboj.7601805)

Dattilo, B.M., Fritz, G., Leclerc, E., Kooi, C.W., Heizmann, C.W., Chazin, W.J. (2007) The Extracellular Region of the Receptor for Advanced Glycation End Products Is Composed of Two Independent Structural Units.  Biochemistry 46, 6957-970. (doi: 10.1021/bi7003735)

Koch, M., Bhattacharya, S., Kehl, T., Gimona, M., Vasák, M., Chazin, W.J., Heizmann, C.W., Kroneck, P.M.H. and Fritz, G. (2007) Implications of Zinc Binding to S100A2. BBA Mol. Cell Res.1473, 457-70. (doi.org/10.1016/j.bbamcr.2006.12.006)

Vgenopoulou, I., Gemperli, A.C., Steuber J. (2006) Specific modification of a Na+ binding site in the NADH:quinone oxidoreductase (NDH-1) from Klebsiella pneumoniae with dicyclohexylcarbodiimide. J. Bacteriol., 188, 3264-32721819

Tao, M., Türk, K., Diez, J., Grütter, M.G., Fritz, G., Steuber, J. (2006) Crystallization of the NADH-oxidizing domain of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae. Acta Cryst. F62, 110-112 (doi: 10.1107/S174430910504306X)

Koch, M., Bhattacharya, S., Kehl, T., Gimona, M., Vasák, M., Chazin, W.J., Heizmann, C.W., Kroneck, P.M.H. and Fritz, G. (2007) Implications of Zinc Binding to S100A2. BBA Mol. Cell Res.1473, 457-70. (doi.org/10.1016/j.bbamcr.2006.12.006) 

Koch, M., Diez, J., and Fritz, G. (2006) Purification and crystallization of the human EF-hand tumor suppressor protein S100A2. Acta Cryst F 62, 1120-3. (doi.org/10.1107/S1744309106039881)

Ostendorp, T., Weibel, M., Leclerc, E., Kleinert, P.; Kroneck, P.M.H., Heizmann, C.W. and Fritz, G. (2006) Expression and purification of the soluble isoform of human receptor of advanced glycation end products using Pichia pastoris. Biochem. Biophys. Res. Comm. 347, 4-11 (doi.org/10.1016/j.bbrc.2006.04.077)

Schiffer, A., Fritz, G., Kroneck, P.M.H., Ermler, U. (2006) Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states. Biochemistry 4, 2960-2967. (doi: 10.1021/bi052168)

Tao, M., Türk, K., Diez, J., Grütter, M.G., Fritz, G., Steuber, J. (2006) Crystallization of the NADH-oxidizing domain of the Na+-translocating NADH:ubiquinone oxidoreductase from Vibrio cholerae. Acta Cryst. F 62, 110-112. (doi: 10.1107/S174430910504306X)

Lin, P.-C., Puhar, A., Türk, K., Piligkos, S., Bill, E., Neese, F., Steuber, J. (2005) A vertebrate-type ferredoxin domain in the Na+ -translocating NADH dehydrogenase from Vibrio cholerae, J. Biol. Chem., 280, 22560 – 22563 (doi:10.1074/jbc.C500171200)

Boiangeou, C.D., Jayamani, E., Brügel, D., Herrmann, G., Kim, J., Forzi, L., Hedderich, R., Vgenopoulou, I., Pierik, A.J., Steuber, J., Buckel, W. (2005) Sodium pumps and hydrogen production in glutamate fermenting anaerobic bacteria, J. Mol. Microbiol. Biotechnol., 10, 105-119 (doi.org/10.1159/000091558)

 Fielding, A.J., Fox, S., Millhauser, G.L., Chattopadhyay, M., Kroneck, P.M., Fritz, G., Eaton, G.R., Eaton, S.S. (2005) Electron spin relaxation of copper(II) complexes in glassy solution between 10 and 120K. J. Magn. Reson. 179, 92-104. (doi.org/10.1016/j.jmr.2005.11.011)

Ostendorp, T., Heizmann, C. W., Kroneck, . P. M. H., and G. Fritz (2005) Purification, crystallization and preliminary X-ray diffraction studies on human Ca2+-binding protein S100B. Acta Cryst. F61,  673-675.(doi.org/10.1107/S1744309105018014)

Fritz, G., Einsle, O., Rudolf, M., Schiffer. A., Kroneck, P.M.H. (2005) Key bacterial multi-centered metal enzymes involved in nitrate and sulfate respiration. J. Mol. Microbiol. Biotechnol. 10, 223-33 (doi:10.1159/000091567)

Türk K., Puhar A., Neese F., Bill E., Fritz G., Steuber J. (2004) NADH oxidation by the Na+ -translocating NADH:quinone oxidoreductase from Vibrio cholerae: functional role of the NqrF subunit, J. Biol. Chem., 279, 21349 – 21355 (doi:10.1074/jbc.M311692200)

Marenholz, I., Heizmann, C.W. and Fritz, G. (2004) S100 proteins in mouse and man: from evolution to function and pathology. Biophys. Biochem. Res. Com. 22, 1111-1122. (doi:10.1016/j.bbrc.2004.07.096)

Gemperli, A.C., Dimroth, P., Steuber, J. (2003) Sodium ion cycling mediates energy coupling between complex I and ATP synthase, Proc. Nat. Acad. Sci. USA 100, 839 – 844 (doi.org/10.1073/pnas.0237328100)

Steuber, J. (2003) The C-terminally truncated NuoL (ND5) subunit of complex I transports Na+, J. Biol. Chem, 278, 26817 – 26822 (doi: 10.1074/jbc.M301682200)

Schmechel, A. , Zentgraf, H.  ,Scheuermann, S. , Fritz, G.  , Pipkorn, R., Reed, J., Beyreuther, K., Bayer, T. A., Multhaup, G. (2003) Alzheimer-amyloid homodimers facilitate Aß fibrillization and the generation of conformational antibodies. J. Biol. Chem. 278, 35317-35324 (doi: 10.1074/jbc.M303547200)

Gemperli, A.C., Dimroth, P., Steuber, J. (2002) The respiratory complex I (NDH I) from Klebsiella pneumoniae, a sodium pump, J. Biol. Chem, 277, 33811 – 33817 (doi: 10.1074/jbc.M204860200)

Steuber, J., Rufibach, M., Fritz, G., Neese, F., Dimroth, P. (2002) Inactivation of the Na+ -translocating NADH:ubiquinone oxidoreductase from Vibrio alginolyticus by reactive oxygen species, Eur. J. Biochem., 269, 1287-1292 (doi.org/10.1046/j.1432-1033.2002.02770.x)

Fritz, G., Mittl, P., Sargent, D.,Vasak,M., Grütter, M.G., Heizmann, C.W. (2002) The Crystal Structure of Apo Human EF-Hand Protein S100A3 at 1.7 Å. J. Biol. Chem.277, 33092-33098 (doi: 10.1074/jbc.M200574200)

Mittl, P., Fritz, G., Sargent, D.,Vasak,M., Grütter, M.G., Heizmann, C.W. (2002) Metal-free MIRAS phasing: Crystal structure of apo-S100A3. Acta Cryst. D58, 1255-1261 (doi.org/10.1107/S0907444902008430)

Fritz, G., Büchert, T., Kroneck, P.M.H. (2002) The function of the [4Fe-4S] clusters and FAD in bacterial and archaeal adenylylsulfate reductases: evidence for flavin catalyzed reduction of adenosine-5'-phosphosulfate. J. Biol. Chem. 277, 26066-26073 (doi: 10.1074/jbc.M203397200)

Kopriva, S., Büchert, T, Fritz, G., Suter, M., Benda, R., Schünemann, V., Koprivova, A., Schurmann, P., Trautwein, A.X., Kroneck, P.M.H., Brunold, C.(2002) The presence of an iron-sulfur cluster in adenosine 5'-phosphosulfate reductase separates organisms utilizing adenosine 5'-phosphosulfate and phosphoadenosine 5'-phosphosulfate for sulfate assimilation. J. Biol. Chem. 277, 21786-21791 (doi: 10.1074/jbc.M202152200)

Fritz, G., Roth, A., Schiffer, A., Büchert, T.,Bourenkov, G., Bartunik, H.D., Huber, H., Stetter, K.O., Kroneck, P.M.H., and Ermler, U. (2002) Structure of adenylylsulfate reductase from the hyperthermophilic Archaeoglobus fulgidus at 1.6 Å resolution. Proc. Natl. Acad. Sci. U S A. 99, 1836-1841 (doi.org/10.1073/pnas.042664399)

Heizmann, C. W., Fritz, G., Schäfer, B. W. (2002) S100 proteins: structure, functions and pathology. Front Biosci. 7, d1356-68 (doi: 10.2741/A846)

Steuber, J. (2001) The Na+ -translocating NADH:quinone oxidoreductase (NDH I) from Klebsiella pneumoniae and Escherichia coli: implications for the mechanism of redox-driven cation translocation by complex I, J. Bioenerg. Biomembr. 33, 179-186

Steuber, J. (2001) Na+ transport by bacterial NADH:quinone oxidoreductases: an extension to the complex I -family of primary redox pumps. Biochim. Biophys. Acta 1505, 45-56 (doi.org/10.1016/S0005-2728(00)00276-0)

Einsle, O., Foerster, S., Mann, K., Fritz, G., Messerschmidt, A., Kroneck, P.M.H. (2001) Spectroscopic investigation and determination of reactivity and structure of the tetraheme cytochrome c3 from Desulfovibrio desulfuricans Essex 6. Eur. J. Biochem. 268, 3028-3035 (doi.org/10.1046/j.1432-1327.2001.02195.x)

Kopriva, S., Büchert, T., Fritz, G., Suter, M., Weber, M., Benda, R., Schaller, J., Feller, U., Schurmann, P., Schünemann, V., Trautwein, A.X., Kroneck, P.M.H., Brunold. C. (2001) Plant adenosine 5'-phosphosulfate reductase is a novel iron-sulfur protein. J. Biol. Chem. 276, 42881-42886. (doi: 10.1074/jbc.M107424200)

Fritz, G., Grießhaber, D., Seth, O., Kroneck, P.M.H. (2001) Nonaheme cytochrome c, a new physiological electron acceptor for [Ni,Fe] hydrogenase in the sulfate-reducing bacterium Desulfovibrio desulfuricans Essex. Primary sequence, molecular parameters and redox properties. Biochemistry 40, 1317-1324 (doi: 10.1021/bi001480+)

Umhau, S., Fritz, G., Diederichs, K., Breed, J., Kroneck, P.M.H., Welte, W. (2001) The three-dimensional structure of nonaheme cytochrome c at 1.89 A resolution. Biochemistry 40, 1308-1316 (doi 10.1021/bi001479a)

Jockel, P., Schmid, M., Steuber, J., Dimroth, P. (2000) A molecular coupling mechanism for the oxaloacetate decarboxylase Na+ pump as inferred from mutational analysis, Biochemistry 39, 2307 – 2315 (doi 10.1021/bi992261v)

Steuber, J., Schmid, C., Rufibach, M., Dimroth, P. (2000) Na+ translocation by complex I (NADH:ubiquinone oxidoreductase) of Escherichia coli, Mol. Microbiol. 35, 428 – 434 (doi.org/10.1046/j.1365-2958.2000.01712.x)

Fritz, G., Büchert, T., Huber, H. Stetter, K.O., Kroneck, P.M.H. (2000) Adenylylsulfate reductase from archaea and bacteria: High similarity in molecular properties emphasizes the central role of the enzyme in sulfur metabolism. FEBS Lett. 473, 63-66. (doi.org/10.1016/S0014-5793(00)01500-3)

Roth, A., Fritz, G., Schiffer, A., Büchert, T., Huber, H., Stetter, K.O., Kroneck, P.M.H., and Ermler U. (2000) Crystallization and preliminary crystallographic analysis of Adenylylsulfate reductase from Archaeoglobus fulgidus. Acta Cryst. D12, 1673-1675. (doi.org/10.1107/S0907444900013366)

Krebs, W., Steuber, J., Gemperli, A., Dimroth, P. (1999) Na+ translocation by the NADH:ubiquinone oxidoreductase (complex I) from Klebsiella pneumoniae, Mol. Microbiol. 33, 590 – 598 (doi.org/10.1046/j.1365-2958.1999.01506.x)

Steuber, J., Krebs, W., Bott, M., Dimroth, P. (1999) A membrane-bound NAD(P)+ -reducing hydrogenase provides reduced pyridine nucleotides during citrate fermentation by Klebsiella pneumoniae, J. Bacteriol. 181, 241 – 245

Steuber, J., Kroneck, P.M.H. (1998) Desulfoviridin, the dissimilatory sulfite reductase from Desulfovibrio desulfuricans (Essex): New structural and functional aspects of the membranous enzyme. Inorg. Chim. Acta 275-276, 52 – 57 (doi.org/10.1016/S0020-1693(97)06143-4)

Fritz, G., Heizmann, C.W., Kroneck, P.M.H (1998) Probing the structure of human and Ca2+- and Zn2+-binding protein S100A3: spectroscopic investigations in its transition metal ion complexes, and three-dimensional structure model. BBA Mol Cell Res. 1448, 264-276. (doi.org/10.1016/S0167-4889(98)00138-4)

Steuber, J., Krebs, W., Dimroth, P. (1997) The Na+ -translocating NADH:ubiquinone oxidoreductase from Vibrio alginolyticus: Redox states of the FAD prosthetic group and mechanism of Ag+ -inhibition. Eur. J. Biochem. 249, 770 – 776 (doi.org/10.1111/j.1432-1033.1997.t01-2-00770.x)

Steuber, J., Arendsen, A.F., Hagen, W.R., Kroneck, P.M.H. (1995) Molecular properties of the dissimilatory sulfite reductase from Desulfovibrio desulfuricans (Essex) and comparison with the enzyme from Desulfovibrio vulgaris (Hildenborough). Eur. J. Biochem. 233, 873-879 (doi.org/10.1111/j.1432-1033.1995.873_3.x)

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